Taking Diclofenac+Paracetamol with alcohol can cause liver damage.

Orthofen 50mg/650mg Tablet is unsafe to use during pregnancy.There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.

Orthofen 50mg/650mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.

Do not drive unless you are feeling well.Orthofen 50mg/650mg Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.

Orthofen 50mg/650mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Orthofen 50mg/650mg Tablet may be needed. Please consult your doctor.

Orthofen 50mg/650mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Orthofen 50mg/650mg Tablet may be needed. Please consult your doctor.However, the use of Orthofen 50mg/650mg Tablet is not recommended in patients with severe liver disease and active liver disease.